pH-responsive release of chlorhexidine from modified nanoporous silica nanoparticles for dental applications
نویسندگان
چکیده
منابع مشابه
pH-Responsive Mesoporous Silica and Carbon Nanoparticles for Drug Delivery
The application of nanotechnology to medicine constitutes a major field of research nowadays. In particular, the use of mesoporous silica and carbon nanoparticles has attracted the attention of numerous researchers due to their unique properties, especially when applied to cancer treatment. Many strategies based on stimuli-responsive nanocarriers have been developed to control the drug release ...
متن کاملGlutathione- and pH-responsive nonporous silica prodrug nanoparticles for controlled release and cancer therapy.
A myriad of drug delivery systems such as liposomes, micelles, polymers and inorganic nanoparticles (NPs) have been developed for cancer therapy. Very few of them, however, have the ability to integrate multiple functionalities such as specific delivery, high circulation stability, controllable release and good biocompatibility and biodegradability in a single system to improve the therapeutic ...
متن کاملPolyaspartic acid-anchored mesoporous silica nanoparticles for pH-responsive doxorubicin release
Background Nanotechnology-based drug delivery systems exhibit promising therapeutic efficacy in cancer chemotherapy. However, ideal nano drug carriers are supposed to be sufficiently internalized into cancer cells and then release therapeutic cargoes in response to certain intracellular stimuli, which has never been an easy task to achieve. Objective This study is to design mesoporous silica ...
متن کاملSurface Immobilization of pH-Responsive Polymer Brushes on Mesoporous Silica Nanoparticles by Enzyme Mimetic Catalytic ATRP for Controlled Cargo Release
Peroxidase mimetic catalytic atom transfer radical polymerization (ATRP) was first used to install tertiary amine-functionalized polymer brushes on the surface of mesoporous silica nanoparticles (MSNs) in a facile and highly efficient manner. Poly(N,N-dimethylaminoethyl methacrylate) (PDMAEMA) brushes-grafted MSNs were fabricated by biocompatible deuteroheminβ-Ala-His-Thr-Val-Glu-Lys (DhHP-6)-c...
متن کاملControlling release from pH-responsive microcapsules.
We report a microfluidic approach to produce monodisperse pH-responsive microcapsules with precisely controlled release behavior. The solid microcapsule shells are composed of a biocompatible pH-responsive polymer and robustly encapsulate an active material; however, when exposed to a trigger pH, the shells degrade and ultimately release the microcapsule contents. We control the trigger pH by u...
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ژورنال
عنوان ژورنال: BioNanoMaterials
سال: 2016
ISSN: 2193-066X,2193-0651
DOI: 10.1515/bnm-2016-0003